Bahauddin Ibraheem Sallout
Women’s Specialized Hospital - King Fahad Medical City, Saudi Arabia
Title: Can MCA Doppler predict mortality in fetuses with congenital hydrocephalus?
Biography
Biography: Bahauddin Ibraheem Sallout
Abstract
Objective: The objective of this study is to investigate the impact of abnormal middle cerebral artery (MCA) Doppler on the
perinatal mortality in fetuses with congenital hydrocephalus (CH).
Methods: A prospective study of all fetuses with CH who delivered at our hospital over a period of 7 years. Data were obtained
from the ultrasound, labor room and intensive neonatal care unit (NICU) database. The perinatal mortality rates were
evaluated in relation to the following measures, associated congenital anomalies, cortical mantle thickness (CMT), and MCA
Doppler abnormalities (absent or reversed diastole). The main outcome measure was perinatal mortality rate in relation to
MCA Doppler changes.
Results: A total of 85 cases of CH were diagnosed and managed. The birth prevalence of CH was 2.44 per 1000 live births. On
one hand, the perinatal mortality rate was higher in those fetuses with non-isolated hydrocephalus, (37.25% (19/51)) versus
(35.29% (12/34), p¼0.854) and in those cases with CMT <10 mm, 38.78% (19/49) versus 33.33% (12/36) in those with CMT
>10 mm, p¼0.607. On the other hand, the perinatal mortality rate was significantly higher in those fetuses with abnormal
MCA Doppler, 100% (13/13) versus 25% (18/72), OR¼0.78, 95% CI (5.52–44085124.60), p<0.001.
Conclusions: Abnormal fetal MCA Doppler (absent or reversed diastole) appears to be a poor prognostic indicator with
significantly high perinatal mortality in fetuses with CH.